NeuroVNN

NeuroVNN models the graph-like nature of brain morphology to produce interpretable indicators from T1-weighted MRI.

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The NeuroVNN project proposes a foundation AI model that leverages coVariance neural networks (VNNs) to capture the graph-theoretic characteristics of brain atrophy from T1-weighted MRI. Trained on healthy adult MRI-derived features and applied to neurodegenerative conditions, the model aims to provide transparent, data-driven biomarkers and visualizations of heterogeneity across and within AD/ADRD. The work addresses limitations of black-box MRI models and supports decision-making for researchers, clinicians, and caregivers.

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