AI-driven Drug Repurposing

The project integrates machine learning with DNA methylation and proteomic data to surface candidate medications that may slow biological aging.

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This project leverages the Mass General Brigham Biobank to screen prescribed medications against blood-based aging biomarkers, then refines candidates through analysis of DNA methylation and plasma proteins. By integrating multiple data types with advanced AI models, the team aims to discover repurposable drugs that consistently show geroprotective signals in real-world data, accelerating translation toward interventions that extend healthspan.

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